CLAD = Canine Leukocyte Adhesion Deficiency also known as Granulocytopathy.
This is an immunity disease, which means the body defence system of the dog is not working properly. This disease affects puppies, causing the death of them. CLAD is not a disease which occurs on adults, but only on pups. CLAD carriers are not dogs who are ill but they can reproduce dogs being ill, affected by CLAD. That's why the DNA testing on CLAD is important.
The past years the FAC has been very active, has always followed, and will always do so, the evolution in the breed. Example of this are the recent developments concerning CLAD. The ISC was one of the first to realize the importance of knowing about CLAD and from the moment the DNA CLAD test became available (test developed in Sweden and England) the ISC was one of the first Irish Setters Clubs (and perhaps was the first) to add it to its breeding rules. On a special breeders meeting this was fully agreed and accepted that it became a rule to test on CLAD before breeding. This started for a period of 5 years from 1.1.2000 on. During that time it was allowed to breed with a carrier but only in combination with a tested CLAD free partner. Together with the ISC and the Veterinary University in Ghent it became possible to do the CLAD DNA test in Belgium.
From 2005 on there should only be bred with animals that are free.